Complete dosage information for PCP — threshold, light, common, strong, and heavy dose ranges across 3 routes of administration.
Full PCP profileImportant Safety Notice
Dosage information is for harm reduction purposes only. Individual sensitivity varies greatly. Always start with the lowest effective dose and work your way up slowly. Never eyeball doses — use a milligram scale.
PCP overdose is a medical emergency that can be fatal. The primary dangers include seizures, respiratory depression, extreme hypertension (which can cause stroke or intracranial hemorrhage), severe hyperthermia, rhabdomyolysis (muscle breakdown leading to kidney failure), and coma. PCP-related deaths have also occurred from trauma during PCP-induced psychosis. Signs of PCP overdose include: seizures, unresponsiveness, extremely high blood pressure, very high body temperature, rapid horizontal or vertical nystagmus (eye movements), muscle rigidity, violent or bizarre behavior, and inability to feel pain (which may lead to self-injury without awareness). Call emergency services (911) immediately. While waiting: do not attempt to restrain the person unless absolutely necessary for safety. Keep them in a quiet, low-stimulation environment. If they are seizing, protect their head. If unresponsive and not breathing, begin CPR. In the emergency department, benzodiazepines are first-line for agitation and seizures. Active cooling is used for hyperthermia. Urine acidification (previously recommended to hasten PCP excretion) is no longer recommended due to the risk of worsening rhabdomyolysis-induced kidney damage. Good Samaritan laws apply.
A common insufflated dose of PCP is 4–8 mg.
The threshold dose for PCP via insufflated is approximately 1 mg.
PCP typically lasts 4–6 hours via insufflated.
PCP can be taken via insufflated, oral, smoked. Each route has different dosage ranges and onset times.