At a Glance
Dosage
oral
| Level | 3C-E | DOI |
|---|---|---|
| Threshold | 20 mg | 0.5 mg |
| Light | 30–40 mg | 0.5–1 mg |
| Common | 40–60 mg | 1–2 mg |
| Strong | 60–80 mg | 2–3 mg |
| Heavy | 80 mg | 3 mg |
Only in 3C-E
insufflated
| Level | Dose |
|---|---|
| Threshold | 15 mg |
Duration
oral
3C-E
oral
Peak
Offset
Afterglow
Onset: 1 hrs – 2 hrsPeak: 4 hrs – 8 hrsOffset: 3 hrs – 6 hrsAfterglow: 3 hrs – 6 hrs
Total: 10 hrs – 16 hrs
DOI
oral
Onset
Come Up
Onset: 1 hrs – 2 hrsCome Up: 1.5 hrs – 3 hrs
Effects
Safety
Interaction: 3C-E + DOI
No direct interaction data available between these substances. This does not mean the combination is safe.
3C-E — Dangerous Interactions
No dangerous interactions recorded.
DOI — Dangerous Interactions
No dangerous interactions recorded.
Frequently Asked Questions
What is the difference between 3C-E and DOI?
3C-E is classified as a Psychedelic (Substituted amphetamines) while DOI is classified as a Psychedelic (Substituted amphetamines). They share 49 effects in common, with 3 effects unique to 3C-E and 4 unique to DOI.
Is it safe to combine 3C-E and DOI?
There is no direct interaction data available for combining 3C-E and DOI. This does not mean the combination is safe. Always exercise caution and research thoroughly.
Which is stronger, 3C-E or DOI?
At common doses via oral, 3C-E is typically dosed at 40–60 mg while DOI is dosed at 1–2 mg. However, "stronger" depends on context — potency, subjective intensity, and duration all factor in. These substances have different pharmacological profiles and comparing raw potency is not straightforward.