At a Glance
| DOI | 1,3-Butanediol | |
|---|---|---|
| Class | Psychedelic | Psychedelic |
| Common Dose (oral) | 1–2 mg | — |
| Total Duration | 2.5–5 hrs | — |
| Routes | oral | oralsublingual |
Dosage
oral
| Level | DOI | 1,3-Butanediol |
|---|---|---|
| Threshold | 0.5 mg | — mg |
| Light | 0.5–1 mg | — mg |
| Common | 1–2 mg | — mg |
| Strong | 2–3 mg | — mg |
| Heavy | 3 mg | — mg |
Only in 1,3-Butanediol
sublingual
| Level | Dose |
|---|
Duration
oral
DOI
oral
Onset
Come Up
Onset: 1 hrs – 2 hrsCome Up: 1.5 hrs – 3 hrs
Total: 16 hrs – 24 hrs
1,3-Butanediol
Only in 1,3-Butanediol
Effects
Shared Effects6
Safety
Interaction: DOI + 1,3-Butanediol
Low Risk & Synergy
Cross-tolerance exists; effects compound
DOI — Dangerous Interactions
No dangerous interactions recorded.
1,3-Butanediol — Dangerous Interactions
No dangerous interactions recorded.
Frequently Asked Questions
What is the difference between DOI and 1,3-Butanediol?
DOI is classified as a Psychedelic (Substituted amphetamines) while 1,3-Butanediol is classified as a Psychedelic (Substituted tryptamines). They share 6 effects in common, with 47 effects unique to DOI and 5 unique to 1,3-Butanediol.
Is it safe to combine DOI and 1,3-Butanediol?
The interaction between DOI and 1,3-Butanediol is classified as "Low Risk & Synergy". Cross-tolerance exists; effects compound Always research interactions thoroughly before combining any substances.
Which is stronger, DOI or 1,3-Butanediol?
Both substances have different dose profiles and pharmacological mechanisms. Comparing "strength" directly is misleading — each has unique effects, durations, and safety considerations.