At a Glance
Dosage
oral
| Level | DOI | 2,5-DMA |
|---|---|---|
| Threshold | 0.5 mg | 10 mg |
| Light | 0.5–1 mg | 10–40 mg |
| Common | 1–2 mg | 40–80 mg |
| Strong | 2–3 mg | 80–200 mg |
| Heavy | 3 mg | 200 mg |
Duration
oral
DOI
oral
Onset
Come Up
Onset: 1 hrs – 2 hrsCome Up: 1.5 hrs – 3 hrs
Total: 16 hrs – 24 hrs
2,5-DMA
Effects
Shared Effects5
Safety
Interaction: DOI + 2,5-DMA
No direct interaction data available between these substances. This does not mean the combination is safe.
DOI — Dangerous Interactions
No dangerous interactions recorded.
2,5-DMA — Dangerous Interactions
Frequently Asked Questions
What is the difference between DOI and 2,5-DMA?
DOI is classified as a Psychedelic (Substituted amphetamines) while 2,5-DMA is classified as a Psychedelic, Stimulants (Amphetamine). They share 5 effects in common, with 48 effects unique to DOI and 2 unique to 2,5-DMA.
Is it safe to combine DOI and 2,5-DMA?
There is no direct interaction data available for combining DOI and 2,5-DMA. This does not mean the combination is safe. Always exercise caution and research thoroughly.
Which is stronger, DOI or 2,5-DMA?
At common doses via oral, DOI is typically dosed at 1–2 mg while 2,5-DMA is dosed at 40–80 mg. However, "stronger" depends on context — potency, subjective intensity, and duration all factor in. These substances have different pharmacological profiles and comparing raw potency is not straightforward.