Datura produces 74 documented subjective effects across 6 categories.
Full Datura profileDatura does not produce an experience so much as it produces a displacement -- a wholesale removal of the user from consensus reality and their installation in a private, terrifying hallucination that masquerades as the real world. The onset is slow and insidious, taking one to three hours to manifest fully. It begins with the anticholinergic signature: extreme dry mouth, the tongue adhering to the palate like leather, pupils dilating until the eyes are mostly black, vision blurring into an impressionist painting where edges dissolve and depth perception collapses. The heart accelerates, pounding with a visible force in the throat and temples.
The transition from baseline to delirium happens without a seam. There is no moment of "it's kicking in," no psychedelic come-up where you feel the ground shift beneath your feet. Instead, reality simply stops being reliable. A friend appears in the room and you speak to them at length before realizing, much later or never, that you are alone. You pick up a phone that does not exist and carry on a detailed conversation. You smoke phantom cigarettes down to phantom filters, one after another, in an endless, unrecognized loop. The hallucinations are not visual overlays on the real world -- they are complete replacements for it, woven with such fidelity that they include tactile sensations, sounds, and contextually appropriate behavior from the imaginary entities populating your field.
At the peak, the distinction between internal and external experience ceases to exist. You might wander through your house performing tasks that have no physical correlate, opening drawers that are not there, walking through doors that are walls. The phantom people are particularly unsettling -- they appear as specific individuals, known to you, behaving in mundane ways that make their unreality all the more disorienting when it is eventually recognized. Spiders and insects are commonly reported, crawling across surfaces or across the skin with a persistence that provokes frantic, futile brushing.
The body, meanwhile, is in crisis. Temperature regulation has collapsed. The skin is flushed and bone-dry. The heart races dangerously. Coordination is so thoroughly compromised that falls and injuries are common, though the dissociative fog of the delirium often prevents any awareness of pain. Urination becomes difficult or impossible. Speech, when attempted, emerges as garbled fragments that bear little relation to the thoughts they were meant to convey.
The duration is punishing -- twelve to thirty-six hours of primary effects, with residual confusion, blurred vision, and perceptual disturbances persisting for days afterward. The comedown is not so much a return to normalcy as a slow, exhausted crawl back toward reality, the mind reassembling its relationship with the physical world piece by piece, haunted by fragmentary memories of conversations with people who were never there.
Abnormal heartbeat (arrhythmia) is any deviation from the heart's normal rhythm — including beats that are too fast (tachycardia), too slow (bradycardia), or irregularly spaced — and represents one of the more medically significant cardiovascular effects of psychoactive substances.
BronchodilationBronchodilation is the widening of the bronchial airways in the lungs, reducing resistance to airflow and producing a subjective sensation of easier, deeper, and more comfortable breathing.
ConstipationA slowing or cessation of bowel movements resulting in difficulty passing stool, commonly caused by opioid receptor activation in the gastrointestinal tract and notoriously resistant to tolerance development.
DehydrationA state of insufficient bodily hydration manifesting as persistent thirst, dry mouth, and physical discomfort, often caused by increased sweating, urination, or simply forgetting to drink water during substance use.
Difficulty urinatingDifficulty urinating, also known as urinary retention, is the experience of being unable to easily pass urine despite a full bladder, commonly caused by stimulant, opioid, and anticholinergic substances that affect bladder muscle control.
DizzinessA sensation of spinning, swaying, or lightheadedness that impairs balance and spatial orientation, often accompanied by nausea and difficulty standing or walking steadily.
Dry mouthA persistent, uncomfortable reduction in saliva production causing the mouth and throat to feel parched, sticky, and difficult to swallow through, commonly known as cottonmouth.
Frequent urinationIncreased urinary frequency beyond normal patterns, caused by diuretic effects or bladder irritation from substances like alcohol, caffeine, and ketamine.
Increased bodily temperatureIncreased bodily temperature (hyperthermia) is an elevation of core body temperature above the normal 37C (98.6F) baseline, caused by substances that increase metabolic rate, impair thermoregulation, or promote sustained physical activity, and representing one of the most dangerous physical effects when severe.
Increased heart rateA noticeable acceleration of heartbeat that can range from a subtle awareness of one's pulse to a forceful, rapid pounding felt throughout the chest, neck, and temples. This effect is among the most commonly reported physiological responses to psychoactive substances and often accompanies stimulation, anxiety, or physical exertion during intoxication.
Increased libidoA marked enhancement of sexual desire, arousal, and sensitivity to erotic stimuli that can range from a gentle heightening of romantic interest to an overwhelming, all-consuming preoccupation with sexual thoughts and physical intimacy. This effect often co-occurs with tactile enhancement and empathy, creating a distinctly sensual state of consciousness.
Motor control lossA distinct decrease in the ability to control one's physical body with precision, balance, and coordination, ranging from minor clumsiness to complete inability to walk.
Muscle crampMuscle cramps are sudden, involuntary, and often painful contractions of muscles that occur as a side effect of certain psychoactive substances, particularly stimulating psychedelics and stimulants.
NauseaAn uncomfortable sensation of queasiness and stomach discomfort that may or may not lead to vomiting, often occurring during the onset phase of many substances.
Nausea suppressionNausea suppression is the pharmacological reduction or elimination of nausea and the urge to vomit, achieved through substances that act on serotonin, dopamine, histamine, or cannabinoid receptors involved in the emetic reflex.
Perception of bodily heavinessPerception of bodily heaviness is the subjective feeling that one's body has become dramatically heavier, resulting in movements feeling sluggish, effortful, and sometimes impossible, as though gravity has selectively increased its pull.
PhotophobiaAn abnormal physical intolerance and sensitivity to light that causes discomfort, squinting, or pain in the eyes, typically linked to substance-induced pupil dilation.
Physical fatiguePhysical fatigue is a state of bodily exhaustion characterized by reduced energy, diminished capacity for physical activity, and an overwhelming desire to rest, commonly experienced during comedowns or as a direct effect of sedating substances.
Pupil dilationA visible enlargement of the pupil diameter (mydriasis) that can range from subtle widening to dramatic saucer-like expansion where the dark pupil dominates the iris. This effect is one of the most recognizable signs of psychedelic and stimulant intoxication and directly contributes to light sensitivity, enhanced color perception, and the characteristic "wide-eyed" appearance.
Respiratory depressionA dangerous slowing and shallowing of breathing that can progress from barely noticeable reductions in respiratory rate to life-threatening cessation of breathing. This is the primary mechanism of death in opioid overdoses and represents one of the most critical safety concerns across all of psychopharmacology.
SedationA state of deep physical and mental calming that manifests as a progressive desire to remain still, lie down, and eventually drift toward sleep. Sedation ranges from a gentle drowsy relaxation to a heavy, irresistible pull into unconsciousness where maintaining wakefulness becomes a losing battle against the body's insistence on shutdown.
SeizureUncontrolled brain electrical activity causing convulsions and loss of consciousness -- a life-threatening medical emergency requiring immediate help.
StimulationA state of heightened physical and mental energy characterized by increased wakefulness, elevated motivation, and a subjective sense of vigor that pervades both body and mind. Users often report feeling electrically alive, with a buzzing readiness to move, talk, and engage that can range from a pleasant caffeine-like lift to an overwhelming, jittery compulsion to act.
Temporary erectile dysfunctionTemporary erectile dysfunction is the substance-induced inability to achieve or sustain a penile erection sufficient for sexual activity, caused by vasoconstriction, sympathetic nervous system overactivation, or altered neurotransmitter signaling, and resolving once the drug's effects wear off.
Vibrating visionVibrating vision is the subjective experience of the visual field rapidly oscillating or shaking due to involuntary eye movements (nystagmus), severely impairing the ability to focus, read, or visually track objects.
The sense of touch becomes dramatically heightened, making physical contact feel intensely pleasurable and detailed. Textures and skin contact produce amplified richness.
Tactile hallucinationTactile hallucinations are convincing physical sensations experienced without any corresponding external stimulus — phantom touches, crawling feelings, vibrations, pressure, temperature changes, or even pain and pleasure that originate entirely within the nervous system.
Tactile suppressionA progressive decrease in the ability to feel physical touch, ranging from mild numbness to complete bodily anaesthesia. The body may feel distant or absent.
A visual phenomenon in which a faint, ghostly imprint of a previously viewed image persists in the visual field after the original stimulus has been removed or one has looked away. These lingering visual echoes are significantly more persistent, vivid, and detailed than normal physiological afterimages, often retaining color and form for several seconds or longer and overlaying themselves onto whatever one currently views.
Brightness alterationPerceived increase or decrease in environmental brightness beyond actual illumination levels, common with stimulants and psychedelics (brightening) or sedatives (darkening).
DiffractionThe experience of seeing rainbow-like spectrums of color and prismatic halos embedded within bright light sources and reflective surfaces, caused by pupil dilation altering how light enters the eye.
Double visionThe visual experience of seeing a single object as two separate, overlapping images, similar to crossing one's eyes, ranging from subtle ghosting to complete inability to perceive fine detail.
DriftingThe visual experience of perceiving stationary objects, textures, and surfaces as appearing to flow, breathe, melt, or shift in position. Drifting is one of the most fundamental and commonly reported visual distortions under the influence of psychedelic substances, serving as the perceptual foundation upon which many other visual effects are built. It manifests as a fluid, organic sense of motion embedded in otherwise static visual fields.
External hallucinationA visual hallucination that manifests within the external environment as though it were physically real, ranging from subtle distortions of existing objects to fully autonomous, detailed scenes and entities that appear indistinguishable from reality.
Internal hallucinationVivid, detailed visual experiences perceived within an imagined mental landscape that can only be seen with closed eyes, ranging from fleeting imagery and abstract scenes to fully immersive, dream-like environments with autonomous narratives and entities.
Object activationA hallucinatory effect in which stationary objects in the environment appear to spontaneously move, animate, or behave as though they possess autonomous will — doors opening by themselves, cups sliding across tables, or furniture assembling and disassembling.
Object alterationA visual effect in which objects in the environment appear to warp, stretch, melt, or animate autonomously, often returning to their original form when the observer looks away and then back.
Perspective hallucinationA hallucinatory phenomenon in which the observer's visual perspective shifts from the normal first-person viewpoint to alternative vantage points — including third-person (seeing oneself from outside), bird's-eye, or omniscient perspectives — during both internal and external hallucinations.
Settings, sceneries, and landscapesThe perceived environment in which hallucinatory experiences take place, ranging from recognizable locations drawn from memory to entirely novel alien landscapes, ancient civilizations, cosmic vistas, and impossible architectural spaces.
Shadow peopleThe perception of dark, humanoid silhouettes lurking in peripheral vision or standing in direct line of sight, appearing to move and behave as autonomous, sentient beings. These entities feel disturbingly real and are a hallmark of deliriant intoxication and sleep deprivation.
Unspeakable horrorsA deeply distressing hallucinatory state involving sustained exposure to nightmarish, terrifying, and personally threatening scenarios — often drawn from the individual's deepest fears — that can occur during high-dose experiences colored by negative emotion.
Visual acuity suppressionVision becomes blurred, indistinct, and out of focus, as though looking through a smudged lens. Fine details degrade and edges lose their definition and sharpness.
Visual hazeA translucent fog or haze overlays the visual field, softening the environment and reducing clarity. May appear colorless or tinted, giving surroundings a dreamlike atmosphere.
A complete or partial inability to form new memories or recall existing ones during and after substance use, ranging from minor gaps in recollection to total blackouts encompassing hours of experience.
AnxietyIntense feelings of apprehension, worry, and dread that can range from a subtle background unease to overwhelming panic attacks with a sense of impending doom, often amplified by the substance's intensification of one's existing mental state.
Cognitive dysphoriaA cognitive and emotional state of intense dissatisfaction, discomfort, and malaise encompassing feelings of depression, irritability, existential unease, and a pervasive sense that something is fundamentally wrong. This is the mental counterpart to physical dysphoria.
Cognitive fatigueMental exhaustion and difficulty sustaining thought after intense cognitive experiences, common during substance comedowns.
ConfusionAn impairment of abstract thinking marked by a persistent inability to grasp or comprehend concepts and situations that would normally be perfectly understandable during sobriety.
DeliriumDelirium is a serious and potentially dangerous state of acute mental confusion involving disorientation, incoherent thought, impaired attention, and frequently vivid hallucinations that the person cannot distinguish from reality. It represents one of the most medically concerning cognitive effects of substance use.
DelusionA delusion is a fixed, false belief that is held with unshakeable certainty and is impervious to contradicting evidence or rational argument — often involving grandiose, persecutory, or bizarre themes that are clearly at odds with observable reality.
DepersonalizationA detachment from one's own sense of self, body, or mental processes, as if observing oneself from outside or feeling that one's actions, thoughts, and identity are automatic and unreal.
DepressionA persistent state of low mood, emotional numbness, hopelessness, and diminished interest or pleasure in activities, often occurring during comedowns, withdrawal, or as a prolonged after-effect of substance use.
DerealizationA perceptual disturbance in which the external world feels profoundly unreal, dreamlike, or artificially constructed, as though experienced through a veil, screen, or foggy barrier separating the observer from reality.
Dream potentiationEnhanced dream vividness, complexity, and recall, often occurring as REM rebound after discontinuing REM-suppressing substances.
Emotion suppressionA blunting or flattening of emotional experience in which feelings become muted, distant, or seemingly absent. The individual may recognize intellectually that they should be feeling something in response to a situation — joy at good news, sadness at a loss, anxiety about a threat — yet the emotional charge simply is not there, as though an invisible pane of glass separates them from their own feelings.
Feelings of impending doomFeelings of impending doom is the sudden onset of an overwhelming, visceral certainty that something terrible is about to happen — often one's own death, a medical crisis, or the end of the world — despite the absence of any rational basis for this belief.
Focus suppressionFocus suppression is a diminished capacity to direct and sustain attention on a chosen target — a task, a thought, a conversation — while successfully ignoring competing stimuli, resulting in persistent distractibility and difficulty completing even simple cognitive activities.
Language suppressionA diminished ability to formulate, comprehend, or articulate language, ranging from difficulty finding the right words to a near-complete inability to construct coherent sentences or understand speech, despite remaining otherwise conscious.
Memory suppressionA dose-dependent inhibition of one's ability to access and utilize short-term and long-term memory, ranging from mild forgetfulness to a profound inability to recall personal identity, biographical information, or the context of the current experience.
Motivation suppressionMotivation suppression is a state of diminished drive and willingness to engage in goal-directed behavior — from everyday tasks like cleaning and working to activities that would normally be experienced as rewarding or enjoyable — sometimes described as a profound and enveloping 'why bother?' feeling.
ParanoiaIrrational suspicion and belief that others are watching, plotting against, or intending harm toward oneself, ranging from mild unease to overwhelming terror.
PsychosisPsychosis is a serious psychiatric state involving a fundamental break from consensus reality — characterized by firmly held false beliefs (delusions), perception of things that are not there (hallucinations), disorganized thought and speech, and a loss of the ability to distinguish internal mental events from external reality.
Sensed presenceSensed presence is the vivid and often unshakeable feeling that an unseen conscious being — whether benevolent, malevolent, neutral, or inscrutable — is present nearby or within one's own mind, despite the complete absence of any visual, auditory, or tactile confirmation.
SleepinessA progressive onset of drowsiness, heaviness, and the desire to sleep that pulls the individual toward rest with increasing insistence. The eyelids feel weighted, the body sinks into whatever surface supports it, cognitive activity winds down into a pleasant fog, and the transition from waking consciousness toward sleep begins to feel not only appealing but inevitable.
Suggestibility enhancementHeightened receptivity to external suggestions, ideas, and influence, commonly experienced during psychedelic and hypnotic states.
Thought decelerationThe experience of thoughts occurring at a markedly reduced pace, as if the mind has been placed into slow motion. Internal dialogue becomes sparse and sluggish, with each idea taking longer to form and process, producing a sense of mental heaviness or cognitive inertia.
Thought disorganizationThought disorganization is a cognitive impairment in which the normal capacity for structured, sequential, and logical thinking becomes significantly disrupted, causing thoughts to become scattered, tangential, and difficult to follow to completion.
Time distortionSubjective perception of time becomes dramatically altered — minutes may feel like hours, or hours pass in moments. Can manifest as either dilation or compression.
WakefulnessAn increased ability to stay awake and alert without the desire to sleep. Distinct from stimulation in that it does not elevate energy above a naturally rested baseline.
Gustatory hallucinations are phantom taste experiences in which distinct flavors manifest in the mouth without any corresponding food, drink, or chemical stimulus. They range from common metallic or chemical tastes to complex, sometimes entirely alien flavor profiles.
Memory replaysMemory replays are vivid, multisensory re-experiences of past events that go far beyond normal recall — the person doesn't just remember an event but relives it as an immersive hallucination, complete with sights, sounds, emotions, and physical sensations from the original experience.
Olfactory hallucinationOlfactory hallucinations (phantosmia) involve the perception of convincing phantom smells — pleasant, foul, or utterly strange — that have no corresponding source in the person's actual environment.
Scenarios and plotsScenarios and plots are the narrative structures that emerge within hallucinatory states — coherent or surreal storylines involving autonomous characters, unfolding events, and immersive settings that can feel as real and consequential as waking life.
Datura can produce 28 physical effects including respiratory depression, increased heart rate, tactile enhancement, tactile suppression, and 24 more.
Yes. Datura can produce 15 visual effects including settings, sceneries, and landscapes, visual acuity suppression, internal hallucination, double vision, and 11 more.
Datura produces 26 cognitive effects including language suppression, thought deceleration, cognitive dysphoria, emotion suppression, and 22 more.