Dissociatives produces 51 documented subjective effects across 7 categories.
Full Dissociatives profileThe dissociative class produces its characteristic effects through blockade of NMDA-type glutamate receptors, creating a progressive disconnection between mind and body that ranges from mild perceptual distortion to complete detachment from external reality.
The general dissociative experience involves progressive numbing of physical sensation, distortion of sound and spatial perception, slowing of thought, and a sense of increasing distance between consciousness and the sensory world. At low doses, the effects resemble a pleasant, dreamlike intoxication. At moderate doses, genuine dissociation occurs: the body becomes remote, the world recedes, and consciousness floats in an intermediate space. At high doses, the characteristic "hole" experience may occur, a state of complete disconnection from all external input during which consciousness inhabits an entirely internal, often vast and abstract, perceptual landscape.
The class spans a wide range of character, from the warm, introspective sedation of ketamine to the stimulated, manic confidence of PCP. Duration varies from less than an hour to many hours. Tolerance develops rapidly with repeated use, and psychological habituation is common.
A distinct decrease in the ability to control one's physical body with precision, balance, and coordination, ranging from minor clumsiness to complete inability to walk.
NauseaAn uncomfortable sensation of queasiness and stomach discomfort that may or may not lead to vomiting, often occurring during the onset phase of many substances.
Orgasm suppressionOrgasm suppression (anorgasmia) is the difficulty or complete inability to achieve orgasm despite adequate sexual stimulation, commonly caused by opioids, dissociatives, SSRIs, and stimulants through mechanisms including tactile suppression, serotonergic excess, and altered CNS signaling.
Pain reliefA suppression of negative physical sensations such as aches and pains, ranging from dulled awareness of discomfort to complete inability to perceive pain.
Perception of bodily lightnessPerception of bodily lightness is the subjective feeling that one's body has become dramatically lighter — sometimes nearly weightless — producing sensations of buoyancy, effortless movement, and a bouncy, energized physical state.
Physical autonomyPhysical autonomy is the experience of one's body performing actions — from simple tasks like walking to complex sequences like cleaning — in an automatic, self-directed manner that requires little to no conscious input or decision-making.
Physical euphoriaAn intensely pleasurable bodily sensation that can manifest as waves of warmth, tingling electricity, or a full-body orgasmic glow radiating outward from the core. This effect is often described as one of the most rewarding physical sensations available through psychoactive substances and is a primary driver of the recreational appeal of many substance classes.
Respiratory depressionA dangerous slowing and shallowing of breathing that can progress from barely noticeable reductions in respiratory rate to life-threatening cessation of breathing. This is the primary mechanism of death in opioid overdoses and represents one of the most critical safety concerns across all of psychopharmacology.
SedationA state of deep physical and mental calming that manifests as a progressive desire to remain still, lie down, and eventually drift toward sleep. Sedation ranges from a gentle drowsy relaxation to a heavy, irresistible pull into unconsciousness where maintaining wakefulness becomes a losing battle against the body's insistence on shutdown.
The visual experience of seeing a single object as two separate, overlapping images, similar to crossing one's eyes, ranging from subtle ghosting to complete inability to perceive fine detail.
Environmental cubismA visual distortion in which the environment and objects within it appear fragmented into geometric, cube-like facets, as if reality has been refracted through a crystalline prism. The effect gives surfaces and three-dimensional space a distinctly angular, Cubist art-like quality reminiscent of Picasso or Braque paintings, where multiple perspectives of the same object are perceived simultaneously.
External hallucinationA visual hallucination that manifests within the external environment as though it were physically real, ranging from subtle distortions of existing objects to fully autonomous, detailed scenes and entities that appear indistinguishable from reality.
Frame rate suppressionPerception of visual motion as choppy discrete frames rather than smooth continuous flow, resembling low-FPS video, most common with dissociatives.
GeometryThe experience of perceiving complex, ever-shifting geometric patterns superimposed over the visual field or visible behind closed eyelids. Geometry is widely considered the hallmark visual effect of psychedelic substances, ranging from simple lattice patterns and honeycombs at low doses to infinitely complex, self-transforming fractal structures at high doses that can feel profoundly meaningful and awe-inspiring.
Internal hallucinationVivid, detailed visual experiences perceived within an imagined mental landscape that can only be seen with closed eyes, ranging from fleeting imagery and abstract scenes to fully immersive, dream-like environments with autonomous narratives and entities.
Perspective distortionsDistortion of perceived depth, distance, and size of real objects, making things appear closer, further, larger, or smaller than they actually are.
Scenery slicingThe visual field fractures into distinct, cleanly cut sections that slowly drift apart from their original positions before resetting, as if reality has been sliced by an invisible blade into geometric pieces that briefly separate and rearrange.
Settings, sceneries, and landscapesThe perceived environment in which hallucinatory experiences take place, ranging from recognizable locations drawn from memory to entirely novel alien landscapes, ancient civilizations, cosmic vistas, and impossible architectural spaces.
Shadow peopleThe perception of dark, humanoid silhouettes lurking in peripheral vision or standing in direct line of sight, appearing to move and behave as autonomous, sentient beings. These entities feel disturbingly real and are a hallmark of deliriant intoxication and sleep deprivation.
Visual acuity suppressionVision becomes blurred, indistinct, and out of focus, as though looking through a smudged lens. Fine details degrade and edges lose their definition and sharpness.
Visual disconnectionA dissociative visual effect involving a progressive detachment from visual perception, ranging from minor suppression and blurring at lower levels to a complete perceptual blackout and immersion in a dark hallucinatory void at higher levels.
A complete or partial inability to form new memories or recall existing ones during and after substance use, ranging from minor gaps in recollection to total blackouts encompassing hours of experience.
Analysis suppressionAnalysis suppression is a cognitive impairment in which the capacity for logical reasoning, critical evaluation, and systematic problem-solving is significantly diminished — leaving the person unable to effectively break down, examine, or draw conclusions about even relatively simple ideas or situations.
AnxietyIntense feelings of apprehension, worry, and dread that can range from a subtle background unease to overwhelming panic attacks with a sense of impending doom, often amplified by the substance's intensification of one's existing mental state.
Autonomous voice communicationAutonomous voice communication is the experience of hearing and engaging in conversation with one or more internal voices that feel genuinely independent from one's own thoughts — capable of expressing novel ideas, holding opinions the person does not share, and carrying on complex dialogue that feels unscripted and spontaneous.
Cognitive euphoriaA cognitive and emotional state of intense well-being, elation, happiness, and joy that manifests as a profound mental contentment and positive outlook. This ranges from gentle feelings of optimism and warmth to overwhelming bliss that pervades all thoughts and perceptions.
Conceptual thinkingA shift in the nature of thought from verbal, linear sentence structures to intuitive, non-linguistic concepts that are felt and understood rather than spoken by an internal narrator.
Deja vuIntense, often prolonged sensation of having already experienced the current moment, common with psychedelics and dissociatives.
DepersonalizationA detachment from one's own sense of self, body, or mental processes, as if observing oneself from outside or feeling that one's actions, thoughts, and identity are automatic and unreal.
DepressionA persistent state of low mood, emotional numbness, hopelessness, and diminished interest or pleasure in activities, often occurring during comedowns, withdrawal, or as a prolonged after-effect of substance use.
DerealizationA perceptual disturbance in which the external world feels profoundly unreal, dreamlike, or artificially constructed, as though experienced through a veil, screen, or foggy barrier separating the observer from reality.
DisinhibitionA marked reduction in social inhibitions, self-consciousness, and behavioral restraint that manifests as increased openness, talkativeness, and willingness to engage in activities one would normally avoid. Users often describe feeling as though an invisible social barrier has been lifted, allowing thoughts and impulses to flow directly into action without the usual filtering process.
Dream potentiationEnhanced dream vividness, complexity, and recall, often occurring as REM rebound after discontinuing REM-suppressing substances.
IntrospectionAn enhanced state of self-reflective awareness in which one feels drawn to examine their own thoughts, emotions, behaviors, and life patterns with unusual depth, clarity, and emotional honesty, often yielding insights that feel therapeutically significant.
Memory suppressionA dose-dependent inhibition of one's ability to access and utilize short-term and long-term memory, ranging from mild forgetfulness to a profound inability to recall personal identity, biographical information, or the context of the current experience.
Personal bias suppressionA decrease in the personal, cultural, and cognitive biases through which one normally filters their perception, enabling more objective self-examination and worldview analysis.
Sensed presenceSensed presence is the vivid and often unshakeable feeling that an unseen conscious being — whether benevolent, malevolent, neutral, or inscrutable — is present nearby or within one's own mind, despite the complete absence of any visual, auditory, or tactile confirmation.
Thought connectivityA state in which disparate thoughts, concepts, and ideas become fluidly and spontaneously interconnected, revealing patterns and relationships that are normally overlooked. The mind weaves together seemingly unrelated subjects into a unified web of associations, often producing novel insights or a profound sense of conceptual coherence.
Thought decelerationThe experience of thoughts occurring at a markedly reduced pace, as if the mind has been placed into slow motion. Internal dialogue becomes sparse and sluggish, with each idea taking longer to form and process, producing a sense of mental heaviness or cognitive inertia.
Thought loopsBecoming trapped in a repeating cycle of thoughts, actions, and emotions that loops every few seconds to minutes. Short-term memory lapses cause the sequence to restart.
Time distortionSubjective perception of time becomes dramatically altered — minutes may feel like hours, or hours pass in moments. Can manifest as either dilation or compression.
Auditory distortion is the experience of sounds becoming warped, pitch-shifted, flanged, or otherwise altered in their perceived qualities without any change to the actual sound source. Familiar sounds may seem alien, stretched in time, or layered with unusual resonances, creating a surreal and sometimes unsettling soundscape that departs significantly from sober auditory perception.
Auditory hallucinationAuditory hallucination is the perception of sounds that have no external source — hearing music, voices, environmental noises, or abstract sonic phenomena that exist entirely within the mind. These range from faint, ambiguous whispers at the edge of perception to fully formed, complex musical compositions or conversational speech that can feel completely real and externally sourced.
Auditory misinterpretationAuditory misinterpretation is the brief, spontaneous misidentification of real sounds as entirely different sounds — ambient noise interpreted as voices, mechanical hums perceived as music, or random environmental sounds heard as words or familiar patterns.
Auditory suppressionA dampening of auditory perception in which sounds become muffled, distant, and reduced in both volume and clarity, as though hearing through thick walls or underwater. This creates a cocoon-like sense of auditory isolation.
Machinescapes are complex multisensory hallucinations involving the perception of enormous mechanical landscapes built from interlocking gears, pulleys, conveyor belts, and other industrial components, often felt as extensions of or replacements for one's own body.
Memory replaysMemory replays are vivid, multisensory re-experiences of past events that go far beyond normal recall — the person doesn't just remember an event but relives it as an immersive hallucination, complete with sights, sounds, emotions, and physical sensations from the original experience.
Scenarios and plotsScenarios and plots are the narrative structures that emerge within hallucinatory states — coherent or surreal storylines involving autonomous characters, unfolding events, and immersive settings that can feel as real and consequential as waking life.
A profound dissolution of the sense of self in which personal identity, memories, and the boundary between self and world completely vanish, leaving only pure undifferentiated awareness.
Unity and interconnectednessA profound sense that identity extends beyond the self to encompass other people, nature, or all of existence. Boundaries between self and other dissolve into felt oneness.
Dissociatives can produce 10 physical effects including respiratory depression, tactile suppression, motor control loss, physical euphoria, and 6 more.
Yes. Dissociatives can produce 12 visual effects including settings, sceneries, and landscapes, visual acuity suppression, environmental cubism, scenery slicing, and 8 more.
Dissociatives produces 20 cognitive effects including personal bias suppression, thought connectivity, thought deceleration, conceptual thinking, and 16 more.