Complete dosage information for Naloxone — threshold, light, common, strong, and heavy dose ranges across 4 routes of administration.
Full Naloxone profileImportant Safety Notice
Dosage information is for harm reduction purposes only. Individual sensitivity varies greatly. Always start with the lowest effective dose and work your way up slowly. Never eyeball doses — use a milligram scale.
overdose, the individual will go through immediate withdrawal. Sudden opioid withdrawal may be life-threatening in extreme cases. Symptoms of opioid withdrawal may include, but are not limited to agitation, nausea, psychosis, temperature regulation suppression, anxiety, physical fatigue, excessive yawning, sweating, dehydration, and pupil dilation. It has been noted that naloxone may be needed in higher dosages depending on the opioid that was consumed. It is not uncommon for several doses of naloxone to be administered in overdose cases involving fentanyl or one of its many analogs. If an individual does not have opioids in their system when naloxone is administered, it may cause dehydration and nausea. It is strongly recommended that one use harm reduction practices when using this substance. Throughout the world, naloxone is not considered a controlled substance. It is a prescription drug in most countries. - **Australia:** In Australia, naloxone is considered an over the counter drug and is available at most pharmacies - **Canada:** In Canada, naloxone kits are distributed at many emergency rooms, clinics, and some pharmacies. - Germany:** Naloxone is a prescription medicine, according to Anlage 1 AMVV. - **Switzerland:** Preparations containing only naloxone are listed as "Abgabekategorie B" pharmaceuticals, which require a prescription to obtain. - **Turkey:** Naloxone is only sold as an addictive to buprenorphine to deter abuse, which is prescription only. - **United States:** At a federal level, naloxone is a prescription drug. Many states have programs that make naloxone over the counter and available at request at most pharmacies. In the United States, most jurisdictions have programs to deploy naloxone to law enforcement and fire and rescue services. - **United Kingdom:** In the United Kingdom, naloxone is considered a prescription drug, but drug services can supply it without a prescription. And anyone can use it to save a life in an emergency. ==See als
A common insufflated dose of Naloxone is 1–4 mg.
Naloxone typically lasts 0.5–1 hours via insufflated.
Naloxone can be taken via insufflated, intramuscular, intravenous, oral. Each route has different dosage ranges and onset times.