At a Glance
Dosage
oral
| Level | MET | DOI |
|---|---|---|
| Threshold | 40 mg | 0.5 mg |
| Light | 60–120 mg | 0.5–1 mg |
| Common | 120–150 mg | 1–2 mg |
| Strong | 150–200 mg | 2–3 mg |
| Heavy | 200 mg | 3 mg |
Only in MET
insufflated
| Level | Dose |
|---|---|
| Threshold | 5 mg |
Duration
oral
MET
oral
Afterglow
Onset: 1 hrs – 2 hrsCome Up: 30 min – 1 hrsPeak: 1.5 hrs – 2.5 hrsOffset: 1 hrs – 3 hrsAfterglow: 6 hrs – 24 hrs
Total: 4 hrs – 6 hrs
DOI
oral
Onset
Come Up
Effects
Safety
Interaction: MET + DOI
Low Risk & Synergy
Cross-tolerance exists; effects compound
MET — Dangerous Interactions
No dangerous interactions recorded.
DOI — Dangerous Interactions
No dangerous interactions recorded.
Frequently Asked Questions
What is the difference between MET and DOI?
MET is classified as a Psychedelic (Substituted tryptamines) while DOI is classified as a Psychedelic (Substituted amphetamines). They share 41 effects in common, with 8 effects unique to MET and 12 unique to DOI.
Is it safe to combine MET and DOI?
The interaction between MET and DOI is classified as "Low Risk & Synergy". Cross-tolerance exists; effects compound Always research interactions thoroughly before combining any substances.
Which is stronger, MET or DOI?
At common doses via oral, MET is typically dosed at 120–150 mg while DOI is dosed at 1–2 mg. However, "stronger" depends on context — potency, subjective intensity, and duration all factor in. These substances have different pharmacological profiles and comparing raw potency is not straightforward.