3-MeO-PCE, a Dissociatives, and 3-HO-PCE, a Dissociatives, are frequently compared by users looking to understand their relative effects, dosage profiles, and safety considerations. Both are classified as Dissociativess, meaning they share a common pharmacological foundation. They share 35 documented effects in common, with 10 effects unique to 3-MeO-PCE and 1 unique to 3-HO-PCE. This side-by-side comparison covers dosage, duration, subjective effects, and safety to help you make informed decisions.
| Effects | 45 documented | 36 documented |
| Interaction | Caution | |
| Level | 3-MeO-PCE | 3-HO-PCE |
|---|---|---|
| Threshold | 2 mg | 5 mg |
| Light | 4–8 mg | 5–10 mg |
| Common | 8–15 mg | 10–15 mg |
| Strong | 15–25 mg | 15–25 mg |
| Heavy | 25 mg | 25 mg |
| Level | Dose |
|---|---|
| Threshold | 1 mg |
| Light | 3–6 mg |
| Common | 6–12 mg |
| Strong | 12–20 mg |
| Heavy | 20 mg |
3-MeO-PCE
Total: 4 hrs – 8 hrs
3-HO-PCE
Total: 3 hrs – 5 hrs
Compounding dissociative effects can cause confusion, mania, and loss of motor control