At a Glance
| GHB | 1,4-Butanediol | |
|---|---|---|
| Class | Depressant | Depressant |
| Common Dose (oral) | 1–2.5 g | 1–2.5 mL |
| Total Duration | 1–2.3 hrs | 1.3–3 hrs |
| Routes | oral | oral |
| Effects | 43 documented | 11 documented |
Dosage
oral
| Level | GHB | 1,4-Butanediol |
|---|---|---|
| Threshold | 0.5 g | 0.5 mL |
| Light | 0.5–1 g | 0.5–1 mL |
| Common | 1–2.5 g | 1–2.5 mL |
| Strong | 2.5–4 g | 2.5–4 mL |
| Heavy | 4 g | 4 mL |
Duration
oral
GHB
oral
Peak
Afterglow
Onset: 5 min – 30 minCome Up: 10 min – 20 minPeak: 45 min – 1.5 hrsOffset: 15 min – 30 minAfterglow: 2 hrs – 4 hrs
Total: 1.5 hrs – 2.5 hrs
1,4-Butanediol
oral
Peak
Effects
Safety
Interaction: GHB + 1,4-Butanediol
No direct interaction data available between these substances. This does not mean the combination is safe.
Frequently Asked Questions
What is the difference between GHB and 1,4-Butanediol?
GHB is classified as a Depressant (Γ-Hydroxy acid) while 1,4-Butanediol is classified as a Depressant (Alkanediol, Diol). They share 9 effects in common, with 34 effects unique to GHB and 2 unique to 1,4-Butanediol.
Is it safe to combine GHB and 1,4-Butanediol?
There is no direct interaction data available for combining GHB and 1,4-Butanediol. This does not mean the combination is safe. Always exercise caution and research thoroughly.
Which is stronger, GHB or 1,4-Butanediol?
At common doses via oral, GHB is typically dosed at 1–2.5 g while 1,4-Butanediol is dosed at 1–2.5 mL. However, "stronger" depends on context — potency, subjective intensity, and duration all factor in. These substances have different pharmacological profiles and comparing raw potency is not straightforward.