At a Glance
| Methadone | Hydromorphone | |
|---|---|---|
| Class | Opioids | Opioids |
| Common Dose (oral) | 5–15 mg | 2–4 mg |
| Total Duration | 6.3–11.5 hrs | 1.3–2.6 hrs |
| Routes | oral | insufflatedintravenous |
Methadone, a Opioids, and Hydromorphone, a Opioids, are frequently compared by users looking to understand their relative effects, dosage profiles, and safety considerations. Both are classified as Opioidss, meaning they share a common pharmacological foundation. They share 17 documented effects in common, with 15 effects unique to Methadone and 0 unique to Hydromorphone. This side-by-side comparison covers dosage, duration, subjective effects, and safety to help you make informed decisions.
| Methadone | Hydromorphone | |
|---|---|---|
| Class | Opioids | Opioids |
| Common Dose (oral) | 5–15 mg | 2–4 mg |
| Total Duration | 6.3–11.5 hrs | 1.3–2.6 hrs |
| Routes | oral | insufflatedintravenous |
| Effects | 32 documented | 17 documented |
| Level | Methadone | Hydromorphone |
|---|---|---|
| Threshold | 1 mg | 0.5 mg |
| Light | 3–5 mg | 1–2 mg |
| Common | 5–15 mg | 2–4 mg |
| Strong | 15–30 mg | 4–8 mg |
| Heavy | 30 mg | 8 mg |
| Level | Dose |
|---|---|
| Threshold | 1 mg |
| Light | 1–2 mg |
| Common | 2–4 mg |
| Strong | 4–8 mg |
| Heavy | 8 mg |
| Level | Dose |
|---|---|
| Threshold | 1 mg |
| Light | 1–2 mg |
| Common | 2–4 mg |
| Strong | 4–6 mg |
| Heavy | 6 mg |
Methadone
Hydromorphone
No direct interaction data available between these substances. This does not mean the combination is safe.