At a Glance
Dosage
oral
| Level | Morphine | Codeine |
|---|---|---|
| Threshold | 10 mg | 30 mg |
| Light | 10–15 mg | 50–100 mg |
| Common | 15–20 mg | 100–150 mg |
| Strong | 20–30 mg | 150–200 mg |
| Heavy | 30 mg | 200 mg |
Only in Morphine
intravenous
| Level | Dose |
|---|---|
| Threshold | 3.33 mg |
Duration
oral
Morphine
oral
Peak
Offset
Onset: 10 min – 30 minCome Up: 20 min – 40 minPeak: 2 hrs – 3 hrsOffset: 1 hrs – 2 hrs
Total: 4 hrs – 6 hrs
Codeine
oral
Come Up
Peak
Offset
Effects
Safety
Interaction: Morphine + Codeine
No direct interaction data available between these substances. This does not mean the combination is safe.
Morphine — Dangerous Interactions
Frequently Asked Questions
What is the difference between Morphine and Codeine?
Morphine is classified as a Opioids (Substituted morphinans) while Codeine is classified as a Opioids (Substituted morphinans). They share 26 effects in common, with 2 effects unique to Morphine and 1 unique to Codeine.
Is it safe to combine Morphine and Codeine?
There is no direct interaction data available for combining Morphine and Codeine. This does not mean the combination is safe. Always exercise caution and research thoroughly.
Which is stronger, Morphine or Codeine?
At common doses via oral, Morphine is typically dosed at 15–20 mg while Codeine is dosed at 100–150 mg. However, "stronger" depends on context — potency, subjective intensity, and duration all factor in. These substances have different pharmacological profiles and comparing raw potency is not straightforward.