At a Glance
Dosage
oral
| Level | Pethidine | Codeine |
|---|---|---|
| Threshold | 25 mg | 30 mg |
| Light | 50–100 mg | 50–100 mg |
| Common | 100–200 mg | 100–150 mg |
| Strong | 200–400 mg | 150–200 mg |
| Heavy | — mg | 200 mg |
Duration
oral
Pethidine
oral
Peak
Afterglow
Onset: 30 min – 1 hrsPeak: 4 hrs – 6 hrsAfterglow: 2 hrs – 10 hrs
Codeine
oral
Come Up
Peak
Offset
Onset: 30 min – 45 minCome Up: 1 hrs – 2 hrs
Effects
Safety
Interaction: Pethidine + Codeine
No direct interaction data available between these substances. This does not mean the combination is safe.
Pethidine — Dangerous Interactions
Frequently Asked Questions
What is the difference between Pethidine and Codeine?
Pethidine is classified as a Opioids (Substituted piperidines) while Codeine is classified as a Opioids (Substituted morphinans). They share 22 effects in common, with 2 effects unique to Pethidine and 5 unique to Codeine.
Is it safe to combine Pethidine and Codeine?
There is no direct interaction data available for combining Pethidine and Codeine. This does not mean the combination is safe. Always exercise caution and research thoroughly.
Which is stronger, Pethidine or Codeine?
At common doses via oral, Pethidine is typically dosed at 100–200 mg while Codeine is dosed at 100–150 mg. However, "stronger" depends on context — potency, subjective intensity, and duration all factor in. These substances have different pharmacological profiles and comparing raw potency is not straightforward.