4-HO-MiPT

4-HO-MiPT (4-hydroxy-N-methyl-N-isopropyltryptamine), known colloquially as miprocin, is a synthetic psychedelic tryptamine in the 4-hydroxy tryptamine family. It is structurally analogous to psilocin (4-HO-DMT) with one methyl group replaced by an isopropyl group, and exists as the active free-phenol form rather than a prodrug. Miprocin has emerged as one of the more respected members of the synthetic 4-HO tryptamine series within the psychedelic research community — valued for a distinctive character that many users describe as particularly visual, introspective, and emotionally resonant.

Community reports, including significant Reddit documentation, characterize 4-HO-MiPT as producing vivid and complex visual phenomena, enhanced music appreciation, emotional warmth, and pronounced introspection. Users frequently note that miprocin has a quality of "lucidity" — the ability to engage thoughtfully with the experience even at moderate doses — that some contrast favorably with the more overpowering character of 4-HO-DMT at comparable doses. The compound has been explored in combination with harmalas (MAO inhibitors) to extend and potentiate the experience, a combination that is pharmacologically significant and requires particular caution.

Duration is typically 4–6 hours. The compound has been used in the context of harm reduction discussions around harm reduction-oriented psychedelic use, with Reddit community members noting its value for introspective and ceremonial contexts. As with all 4-HO tryptamines, it acts directly at serotonin 5-HT2A receptors without requiring prodrug conversion.