How long does DiPT last?

The total duration of DiPT via oral is 3 hours to 6 hours. Onset typically occurs within 30 minutes to 1 hour.

DiPT — SubstanceWiki

Q: What is DiPT?

Psychedelic drug Diisopropyltryptamine (DiPT), also known as N,N-diisopropyltryptamine, is a psychedelic drug of the tryptamine family related to dimethyltryptamine (DMT). It is unusual among psychedelics in that at usual doses it primarily or exclusively produces strong auditory changes, including

DiPT

Substituted tryptamines · Psychedelic

Psychedelic(Substituted tryptamines)

Quick Dosage

oral30–75 mg (common)

smoked15–20 mg (common)

Total duration (oral)3hr–6hr

View full details

Diisopropyltryptamine (DiPT), also known as N,N-diisopropyltryptamine, is a psychedelic drug of the tryptamine family related to dimethyltryptamine (DMT). It is unusual among psychedelics in that at usual doses it primarily or exclusively produces strong auditory changes, including decreased pitch, harmonic distortion, and sound unfamiliarity, but produces no other hallucinogenic effects such as visuals. However, the drug may produce more classically psychedelic effects at very high doses. It is taken orally, but can also be smoked.

The drug acts as a serotonin receptor agonist, including of the serotonin 5-HT2A, 5-HT2B, and 5-HT2C receptors. It has weak activity at the serotonin 5-HT1A receptor. DiPT does not appear to bind to the serotonin 5-HT6 receptor or to several other serotonin receptors. It produces psychedelic-like effects in animals, which appear to be mediated primarily by serotonin 5-HT2A receptor activation. The mechanisms by which DiPT produces selective auditory changes are unknown. Derivatives of DiPT include 4-HO-DiPT (iprocin) and 5-MeO-DiPT (foxy methoxy), among others.

DiPT was first described in the scientific literature by 1959. The basic properties of DiPT in humans were described by Alexander Shulgin in 1976 and its effects were described in detail by Shulgin in subsequent publications in the 1980s and in his 1997 book TiHKAL (Tryptamines I Have Known and Loved). DiPT was encountered as a novel designer drug in 2005. However, it appears to be little-used recreationally compared to other psychedelic drugs, perhaps due to its unusual effects.

How It Feels

The onset of DiPT is unlike any other psychedelic, because its primary theatre of operation is the auditory system. Within thirty to sixty minutes of ingestion, sounds begin to change. The shift is subtle at first — a faint metallic edge to voices, a slight hollowness in ambient noise — but it progresses steadily into territory that is genuinely without parallel in the psychedelic pharmacopoeia. Physically, the onset is relatively benign: mild body warmth, occasional nausea, and a slight restlessness, but nothing that would prepare the user for what is about to happen to their hearing.

As the come-up continues, the auditory distortions deepen and become unmistakable. Pitch drops. Voices become lower, slower, and more resonant, as though everyone is speaking from the bottom of a well. Music becomes deeply alien — melodies that have been heard a thousand times are suddenly performed in a key that does not exist, with instruments that sound as though they have been rebuilt from unfamiliar materials. Higher-pitched sounds are affected most dramatically, dropping by a semitone, a whole tone, or even more. The effect is profoundly disorienting because hearing is one of the most deeply anchored perceptual systems; we rely on it for social connection, spatial orientation, and emotional calibration, and DiPT disrupts all of these simultaneously.

At the peak, typically two to three hours in and lasting three to four hours, the pitch shifting is fully established and inescapable. Conversation becomes surreal — the user hears their own voice at an unfamiliar pitch, and other voices are so altered that identifying speakers by sound alone can be difficult. Environmental sounds — traffic, birdsong, running water — become strange and unfamiliar. Remarkably, visual effects are almost entirely absent at common doses; the experience is almost purely auditory. The headspace is clear and relatively unaltered, which creates a strange juxtaposition: a sober, lucid mind inhabiting a world that sounds completely wrong.

The comedown is gradual, with pitch slowly normalizing over three to six hours after the peak. In some cases, a residual pitch shift can persist for days — a lingering flatness to sounds that slowly resolves. The total active duration is eight to twelve hours, and there is little visual or emotional afterglow. What lingers instead is a profound awareness of how much of ordinary experience is constructed from auditory information, and how completely reality can be destabilized by altering nothing but the frequency at which the world is heard.

Pharmacology

The psychedelic effects of DiPT are believed to come from its efficacy at the 5-HT2A receptor. DiPT also has notable binding affinities at the dopamine receptors, adrenergic receptors, and the serotonin, dopamine, and norepinephrine transport sites. However, the role of these interactions and how they result in the psychedelic experience remains subject to on-going scientific investigation.

Although DiPT's effects are primarily auditory, some users have reported lack of coordination or balance,stomach bloating,confusion, and visual distortions at higher doses. Aside from these, the most prevalent non-auditory effect is inner ear pressure (which has been painful in some instances such as when combined with MDMA).

One experiment involving subjects with perfect pitch indicated that there is no clear relationship between perceived pitch and actual pitch.

Although recent unpublished research has examined the role of DiPT in hearing perception in rodents, it is not clear that the auditory effect is preserved in nonhuman species; this finding indicates that DiPT does not produce effects similar to other tryptamine psychedelics such as DPT and 5-MeO-DMT in acoustic startle reflex paradigms. DiPT still remains widely unexplored.

The toxicity and long-toxic dose is unknown. This is because DiPT is a research chemical with very little history of human usage.

Anecdotal reports from those who have tried DiPT suggests that there are no negative health effects attributed to simply trying the drug by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.

It is strongly recommended that one use harm reduction practices when using this drug.

As with many psychedelics, the use of DiPT has the potential to bring about long-lasting perceptual and psychological alterations. DiPT is known to chronically alter the perception of sound and talking, which may not be suitable for everyone. -not habit-forming and the desire to use it can actually decrease with use. It is most often self-regulating.almost immediately after ingestion. After that,37 days to be back at baseline (in the absence of further consumption). DiPT presents cross-tolerance with Cross-all psychedelics, meaning that after the consumption of DiPT all psychedelics will have a reduced effect.

Germany: DiPT is controlled under the NpSG (New Psychoactive Substances Act) as of July 18, 2019. Production and import with the aim to place it on the market, administration to another person and trading is punishable. Possession is illegal but not penalized.
Latvia: DiPT is a Schedule I controlled substance.
New Zealand: DiPT is an analogue of DMT, so is a Class C controlled controlled substance in New Zealand.
**Sweden:**Sweden's public health agency suggested classifying DiPT as a hazardous substance, on May 15, 2019.
Switzerland: DiPT is not controlled under Buchstabe A, B, C and D. It could be considered legal.
United Kingdom: DiPT is a Class A controlled substance in the United Kingdom as a result of the tryptamine catch-all clause.
United States: DiPT is unscheduled in the United States. It may be considered an analogue of DET, a Schedule I compound under the Controlled Substances Act. As such, the sale for human consumption or the use for illicit non-medical or industrial intents and purposes could be prosecuted as crimes under the Federal Analogue Act.
Florida: DiPT is a Schedule I controlled substance in the state of Florida. It is illegal to buy, sell, or possess.
Responsible use
Tryptamine
Psychedelic
DMT
DPT
DiPT (Wikipedia)
DiPT (Erowid Vault)
DiPT (TiHKAL / Isomer Design)
Discussion
The Big & Dandy DiPT Thread (Bluelight)

Detection Methods

Urine Detection

DiPT is not targeted by standard immunoassay-based urine drug screens. As a tryptamine, it is metabolized through monoamine oxidase pathways and produces hydroxylated and deaminated metabolites that are excreted renally. Specialized LC-MS/MS methods can detect tryptamine metabolites in urine for approximately 24 to 48 hours after ingestion. The short duration of action of most base tryptamines results in a relatively brief detection window compared to longer-acting psychoactive substances.

Blood and Serum Detection

Blood detection windows for DiPT are short, typically 4 to 12 hours after oral administration. If smoked or insufflated, peak concentrations occur within minutes and clearance is more rapid. LC-MS/MS is required for reliable blood detection at the low concentrations characteristic of tryptamine compounds. The rapid metabolism by MAO-A significantly limits the time window in which blood sampling can capture meaningful concentrations.

Standard Drug Panel Inclusion

DiPT is NOT included on standard 5-panel, 10-panel, or 12-panel drug screens. Tryptamines do not cross-react with immunoassay targets for amphetamines, cannabinoids, cocaine metabolites, opiates, PCP, or any other standard panel analyte. Detection requires specific testing at a reference laboratory capable of novel psychoactive substance analysis. Even extended clinical panels rarely include base tryptamines.

Confirmatory Methods

Confirmatory identification of DiPT relies on LC-MS/MS or GC-MS with appropriate reference standards. GC-MS analysis of tryptamines may require derivatization for optimal sensitivity and chromatographic performance. Reference laboratories specializing in novel psychoactive substances provide the most comprehensive detection capabilities. Standard clinical toxicology laboratories generally do not maintain validated methods for base tryptamines.

Reagent Testing (Harm Reduction)

The Ehrlich reagent produces a purple to violet reaction with DiPT, confirming the presence of an indole ring system. This is the primary field identification tool and should be used as the first screening test. The Hofmann reagent provides a confirmatory blue to purple reaction. The Marquis reagent typically shows no reaction or a slight brown-yellow discoloration with base tryptamines. A positive Ehrlich result confirms the tryptamine class but does not identify the specific compound. Multiple reagents should be used together for greater confidence in identification.

Interactions

Substance	Status	Note
2-Aminoindane	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
2-FA	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
2-FEA	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
2-FMA	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
2,5-DMA	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
2C-H	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
3-FA	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
3-FEA	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
3-FMA	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
3-FPM	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
3-MMC	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
3,4-CTMP	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
4-FA	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
4-FMA	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
4-MMC	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
4F-EPH	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
4F-MPH	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
5-APB	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
5F-AKB48	Caution	Cannabis can unpredictably intensify psychedelic effects and increase anxiety
5F-PB-22	Caution	Cannabis can unpredictably intensify psychedelic effects and increase anxiety
6-APDB	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
8-Chlorotheophylline	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
A-PHP	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
A-PVP	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
AB-FUBINACA	Caution	Cannabis can unpredictably intensify psychedelic effects and increase anxiety
Adrafinil	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Amphetamine	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Anandamide	Caution	Cannabis can unpredictably intensify psychedelic effects and increase anxiety
APICA	Caution	Cannabis can unpredictably intensify psychedelic effects and increase anxiety
Armodafinil	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Atropa belladonna	Caution	Unpredictable compounding of hallucinogenic effects with anticholinergic delirium
Benzydamine	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Bromantane	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Butylone	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Caffeine	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Cannabidiol	Caution	Cannabis can unpredictably intensify psychedelic effects and increase anxiety
Cannabis	Caution	Cannabis can unpredictably intensify psychedelic effects and increase anxiety
Cocaine	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Cyclazodone	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Datura	Caution	Unpredictable compounding of hallucinogenic effects with anticholinergic delirium
Desoxypipradrol	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Dextroamphetamine	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Dichloropane	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Diphenhydramine	Caution	Unpredictable compounding of hallucinogenic effects with anticholinergic delirium
Ephedrine	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Ephylone	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
ETH-CAT	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Ethylone	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Ethylphenidate	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Fenethylline	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Harmala alkaloid	Caution	MAOIs dramatically potentiate psychedelics; drastically reduce dose and exercise extreme caution
Hexedrone	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Isopropylphenidate	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
JWH-018	Caution	Cannabis can unpredictably intensify psychedelic effects and increase anxiety
JWH-073	Caution	Cannabis can unpredictably intensify psychedelic effects and increase anxiety
Kratom	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Lisdexamfetamine	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
MAOI	Caution	MAOIs dramatically potentiate psychedelics; drastically reduce dose and exercise extreme caution
MCPP	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
MDA	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
MDMA	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
MDPV	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Mephedrone	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Methamphetamine	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Methcathinone	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Methiopropamine	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Methylnaphthidate	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Methylone	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Methylphenidate	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Mexedrone	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Mirtazapine	Caution	Unpredictable compounding of hallucinogenic effects with anticholinergic delirium
Modafinil	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Myristicin	Caution	Unpredictable compounding of hallucinogenic effects with anticholinergic delirium
N-Ethylhexedrone	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
N-Methylbisfluoromodafinil	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
NEP	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Nicotine	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
NM-2-AI	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Oxiracetam	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Peganum harmala	Caution	MAOIs dramatically potentiate psychedelics; drastically reduce dose and exercise extreme caution
Pentedrone	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Phenylpiracetam	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
Rhodiola Rosea	Caution	Increases anxiety, cardiovascular stress, and psychological intensity
1,3-Butanediol	Low Risk & Synergy	Cross-tolerance exists; effects compound
1B-LSD	Low Risk & Synergy	Cross-tolerance exists; effects compound
1cP-AL-LAD	Low Risk & Synergy	Cross-tolerance exists; effects compound
1cP-LSD	Low Risk & Synergy	Cross-tolerance exists; effects compound
1cP-MiPLA	Low Risk & Synergy	Cross-tolerance exists; effects compound
1P-ETH-LAD	Low Risk & Synergy	Cross-tolerance exists; effects compound
1P-LSD	Low Risk & Synergy	Cross-tolerance exists; effects compound
1V-LSD	Low Risk & Synergy	Cross-tolerance exists; effects compound
2-Fluorodeschloroketamine	Low Risk & Synergy	Produces unique synergistic effects; often combined
25B-NBOH	Low Risk & Synergy	Cross-tolerance exists; effects compound
25B-NBOMe	Low Risk & Synergy	Cross-tolerance exists; effects compound
25C-NBOH	Low Risk & Synergy	Cross-tolerance exists; effects compound
25C-NBOMe	Low Risk & Synergy	Cross-tolerance exists; effects compound
25D-NBOMe	Low Risk & Synergy	Cross-tolerance exists; effects compound
25E-NBOH	Low Risk & Synergy	Cross-tolerance exists; effects compound
25I-NBOH	Low Risk & Synergy	Cross-tolerance exists; effects compound
25I-NBOMe	Low Risk & Synergy	Cross-tolerance exists; effects compound
25N-NBOMe	Low Risk & Synergy	Cross-tolerance exists; effects compound
2C-B	Low Risk & Synergy	Cross-tolerance exists; effects compound
2C-B-FLY	Low Risk & Synergy	Cross-tolerance exists; effects compound
2C-C	Low Risk & Synergy	Cross-tolerance exists; effects compound
2C-D	Low Risk & Synergy	Cross-tolerance exists; effects compound
2C-E	Low Risk & Synergy	Cross-tolerance exists; effects compound
2C-I	Low Risk & Synergy	Cross-tolerance exists; effects compound
2C-P	Low Risk & Synergy	Cross-tolerance exists; effects compound
2C-T	Low Risk & Synergy	Cross-tolerance exists; effects compound
2C-T-2	Low Risk & Synergy	Cross-tolerance exists; effects compound
2C-T-21	Low Risk & Synergy	Cross-tolerance exists; effects compound
2C-T-7	Low Risk & Synergy	Cross-tolerance exists; effects compound
3-Cl-PCP	Low Risk & Synergy	Produces unique synergistic effects; often combined
3-HO-PCE	Low Risk & Synergy	Produces unique synergistic effects; often combined
3-HO-PCP	Low Risk & Synergy	Produces unique synergistic effects; often combined
3-MeO-PCE	Low Risk & Synergy	Produces unique synergistic effects; often combined
3-MeO-PCMo	Low Risk & Synergy	Produces unique synergistic effects; often combined
3-MeO-PCP	Low Risk & Synergy	Produces unique synergistic effects; often combined
3C-E	Low Risk & Synergy	Cross-tolerance exists; effects compound
3C-P	Low Risk & Synergy	Cross-tolerance exists; effects compound
4-AcO-DET	Low Risk & Synergy	Cross-tolerance exists; effects compound
4-AcO-DiPT	Low Risk & Synergy	Cross-tolerance exists; effects compound
4-AcO-DMT	Low Risk & Synergy	Cross-tolerance exists; effects compound
4-AcO-MET	Low Risk & Synergy	Cross-tolerance exists; effects compound
4-AcO-MiPT	Low Risk & Synergy	Cross-tolerance exists; effects compound
4-HO-DET	Low Risk & Synergy	Cross-tolerance exists; effects compound
4-HO-DiPT	Low Risk & Synergy	Cross-tolerance exists; effects compound
4-HO-DPT	Low Risk & Synergy	Cross-tolerance exists; effects compound
4-HO-EPT	Low Risk & Synergy	Cross-tolerance exists; effects compound
4-HO-MET	Low Risk & Synergy	Cross-tolerance exists; effects compound
4-HO-MiPT	Low Risk & Synergy	Cross-tolerance exists; effects compound
4-HO-MPT	Low Risk & Synergy	Cross-tolerance exists; effects compound
4-MeO-PCP	Low Risk & Synergy	Produces unique synergistic effects; often combined
5-MeO-DALT	Low Risk & Synergy	Cross-tolerance exists; effects compound
5-MeO-DiBF	Low Risk & Synergy	Cross-tolerance exists; effects compound
5-MeO-DiPT	Low Risk & Synergy	Cross-tolerance exists; effects compound
5-MeO-DMT	Low Risk & Synergy	Cross-tolerance exists; effects compound
5-MeO-MiPT	Low Risk & Synergy	Cross-tolerance exists; effects compound
6-APB	Low Risk & Synergy	Cross-tolerance exists; effects compound
AL-LAD	Low Risk & Synergy	Cross-tolerance exists; effects compound
ALD-52	Low Risk & Synergy	Cross-tolerance exists; effects compound
Allylescaline	Low Risk & Synergy	Cross-tolerance exists; effects compound
Ayahuasca	Low Risk & Synergy	Cross-tolerance exists; effects compound
Bromo-DragonFLY	Low Risk & Synergy	Cross-tolerance exists; effects compound
Bufotenin	Low Risk & Synergy	Cross-tolerance exists; effects compound
Deschloroketamine	Low Risk & Synergy	Produces unique synergistic effects; often combined
DET	Low Risk & Synergy	Cross-tolerance exists; effects compound
Dextromethorphan	Low Risk & Synergy	Produces unique synergistic effects; often combined
Diphenidine	Low Risk & Synergy	Produces unique synergistic effects; often combined
DMT	Low Risk & Synergy	Cross-tolerance exists; effects compound
DOB	Low Risk & Synergy	Cross-tolerance exists; effects compound
DOC	Low Risk & Synergy	Cross-tolerance exists; effects compound
DOI	Low Risk & Synergy	Cross-tolerance exists; effects compound
DOM	Low Risk & Synergy	Cross-tolerance exists; effects compound
DPT	Low Risk & Synergy	Cross-tolerance exists; effects compound
Efavirenz	Low Risk & Synergy	Cross-tolerance exists; effects compound
Ephenidine	Low Risk & Synergy	Produces unique synergistic effects; often combined
EPT	Low Risk & Synergy	Cross-tolerance exists; effects compound
Escaline	Low Risk & Synergy	Cross-tolerance exists; effects compound
ETH-LAD	Low Risk & Synergy	Cross-tolerance exists; effects compound
HXE	Low Risk & Synergy	Produces unique synergistic effects; often combined
Ibogaine	Low Risk & Synergy	Cross-tolerance exists; effects compound
Inhalants	Low Risk & Synergy	Produces unique synergistic effects; often combined
Ketamine	Low Risk & Synergy	Produces unique synergistic effects; often combined
LAE-32	Low Risk & Synergy	Cross-tolerance exists; effects compound
LSA	Low Risk & Synergy	Cross-tolerance exists; effects compound
LSD	Low Risk & Synergy	Cross-tolerance exists; effects compound
LSM-775	Low Risk & Synergy	Cross-tolerance exists; effects compound
LSZ	Low Risk & Synergy	Cross-tolerance exists; effects compound
Memantine	Low Risk & Synergy	Produces unique synergistic effects; often combined
Mescaline	Low Risk & Synergy	Cross-tolerance exists; effects compound
MET	Low Risk & Synergy	Cross-tolerance exists; effects compound
Methallylescaline	Low Risk & Synergy	Cross-tolerance exists; effects compound
Methoxetamine	Low Risk & Synergy	Produces unique synergistic effects; often combined
Methoxphenidine	Low Risk & Synergy	Produces unique synergistic effects; often combined
MiPLA	Low Risk & Synergy	Cross-tolerance exists; effects compound
MiPT	Low Risk & Synergy	Cross-tolerance exists; effects compound
MPT	Low Risk & Synergy	Cross-tolerance exists; effects compound
MXiPr	Low Risk & Synergy	Produces unique synergistic effects; often combined
Nitrous	Low Risk & Synergy	Produces unique synergistic effects; often combined
O-PCE	Low Risk & Synergy	Produces unique synergistic effects; often combined
PARGY-LAD	Low Risk & Synergy	Cross-tolerance exists; effects compound
PCE	Low Risk & Synergy	Produces unique synergistic effects; often combined
PCP	Low Risk & Synergy	Produces unique synergistic effects; often combined
PRO-LAD	Low Risk & Synergy	Cross-tolerance exists; effects compound
Psilocybin Mushrooms	Low Risk & Synergy	Cross-tolerance exists; effects compound
Codeine	Low Risk & No Synergy	No significant pharmacological interaction; opioids may slightly dull the psychedelic experience
Fentanyl	Low Risk & No Synergy	No significant pharmacological interaction; opioids may slightly dull the psychedelic experience
Heroin	Low Risk & No Synergy	No significant pharmacological interaction; opioids may slightly dull the psychedelic experience
Morphine	Low Risk & No Synergy	No significant pharmacological interaction; opioids may slightly dull the psychedelic experience
Oxycodone	Low Risk & No Synergy	No significant pharmacological interaction; opioids may slightly dull the psychedelic experience
Alcohol	Low Risk & Decrease	Depressants dull psychedelic effects; benzodiazepines are commonly used as trip-killers
Alprazolam	Low Risk & Decrease	Depressants dull psychedelic effects; benzodiazepines are commonly used as trip-killers
Clonazepam	Low Risk & Decrease	Depressants dull psychedelic effects; benzodiazepines are commonly used as trip-killers
Diazepam	Low Risk & Decrease	Depressants dull psychedelic effects; benzodiazepines are commonly used as trip-killers
GHB	Low Risk & Decrease	Depressants dull psychedelic effects; benzodiazepines are commonly used as trip-killers
Lorazepam	Low Risk & Decrease	Depressants dull psychedelic effects; benzodiazepines are commonly used as trip-killers

Showing 197 key interactions out of 240 total.

Toxicity & Safety

Further information: Research chemicals § Toxicity and harm potential, and Responsible use § Hallucinogens The toxicity and long-term health effects of recreational DiPT do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because DiPT is a research chemical with very little history of human usage.

It is strongly recommended that one use harm reduction practices when using this drug.

Dependence and abuse potential

DiPT is not habit-forming and the desire to use it can actually decrease with use. It is most often self-regulating.

Tolerance to the effects of DiPT is built almost immediately after ingestion. After that, it takes about 3 days for the tolerance to be reduced to half and 7 days to be back at baseline (in the absence of further consumption). DiPT presents cross-tolerance with all psychedelics, meaning that after the consumption of DiPT all psychedelics will have a reduced effect.

Addiction Potential

not habit-forming

Overdose Information

Fatal overdose from DiPT alone, at doses within the typical recreational range, is extremely unlikely based on the available evidence for classical psychedelics. The therapeutic index for most psychedelics is very wide.

However, psychological emergencies can occur and require appropriate response:

Severe anxiety, panic, or psychotic episodes
Dangerous behavior due to impaired reality testing
Self-harm in the context of a distressing experience

Emergency management: If someone is experiencing a severe adverse reaction, move them to a calm, quiet environment. Speak reassuringly. Do not restrain unless there is immediate danger. Benzodiazepines (if available and the person is conscious and able to swallow) can reduce acute anxiety. If psychotic symptoms, self-harm risk, or medical distress is present, seek emergency medical attention.Medical attention: Seek help immediately for seizures, extremely elevated body temperature, signs of serotonin syndrome (agitation, tremor, diarrhea, rapid heart rate), or if the substance consumed is uncertain.

DiPT

Quick Dosage

Dosage

oral

smoked

Duration

oral

smoked

How It Feels

Subjective Effects

Physical Effects

Physical(7)

Tactile(1)

Cognitive & Perceptual Effects

Visual(3)

Cognitive(4)

Pharmacology

Detection Methods

Urine Detection

Blood and Serum Detection

Standard Drug Panel Inclusion

Confirmatory Methods

Reagent Testing (Harm Reduction)

Interactions

History

Harm Reduction

Toxicity & Safety

Addiction Potential

Overdose Information

Tolerance

Cross-tolerances

Legal Status

Experience Reports (3)

Tips (7)

Community Discussions (1)

See Also

References (6)

Frequently Asked Questions

Auditory(3)

Multi-sensory(1)

Transpersonal(1)